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Medchemexpress LLC 6H-Thieno[3,2-f]triazolo[4,3-a]diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-trimethyl-, cyclopropyl ester, (6S)- | 3077900-08-1 | 98.3% | 440.95 | 5 MG

Supplier: Medchemexpress LLC HY1764385MG
DDL-357 is a potent enhancer of secreted clusterin. It has been shown to reduce phospho-tau levels in the brain and improve memory in the murine 3xTg-AD model. It is intended for research use only and not for sale to patients.
- Purity: 98.31%
- Appearance: Solid
- Color: White to off-white
- Shipping: Room temperature in continental US; may vary elsewhere.
- Storage (powder): -20°C for 3 years, 4°C for 2 years.
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month.
- Solubility (in vitro): 100 mg/mL in DMSO (226.78 mM; requires ultrasonic, hygroscopic DMSO affects solubility).
- Solubility (in vivo - protocol 1): ≥ 5 mg/mL (11.34 mM) in a mixture of 10% DMSO, 40% PEG300, 5% Tween-80, and 45% Saline, yielding a clear solution.
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