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Medchemexpress LLC 6PPD-Q | 2754428-18-5 | C18H22N2O2 | 25 MG
Supplier: Medchemexpress LLC 25MGHY153169
6PPD-Q (6PPD-Quinone) is an environmental pollutant detected in human urine and widely present in the environment. It targets and binds to CNR2, CNR1, AA2AR, LCAT, and TRPA1, with CNR2 showing the highest binding affinity, potentially acting as a CNR2 receptor agonist to activate cannabinoid receptors. It can induce intestinal inflammation and barrier damage by disrupting mitochondrial function, reducing neuronal glycolysis metabolites and TCA cycle intermediates, and exacerbating α-synuclein (α-syn) aggregation. This compound is applicable for research in environmental toxicology, neurodegenerative diseases, and inflammation-related disorders.
- Targets and binds to CNR2, CNR1, AA2AR, LCAT, and TRPA1
- Acts as a CNR2 receptor agonist
- Induces intestinal inflammation and barrier damage
- Reduces neuronal glycolysis metabolites and TCA cycle intermediates
- Exacerbates α-synuclein (α-syn) aggregation
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