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Ubpbio N-terminally 6xHis-tagged recombinant human UbC13/UEV1A (UbE2N), a ubiquitin conjugating enzyme catalyzing formation of K63 polyubiquitin chains
Supplier: Ubpbio C3200
UbE2N (Ubc13/UEV1A) is a complex that acts as an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. Uev1a must interact with Ubc13 because it lacks the active site that other E2s posses. Ube2N has been known to catalyze K63 – linked Ub chains which aides in activation of kinases in NF – kappaB signaling pathway, amongst other tasks.
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