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Medchemexpress LLC 7-(2-morpholin-4-ylethoxy)-4-(2-pyridin-2-yl-dihydropyrrolopyrazol-3-yl)quinoline | 700874-71-1 | 100.0% | 100 MG
SDP

Catalog No. 5000230400
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LY2109761 is an orally active, small-molecule dual inhibitor of transforming growth factor-β (TGF-β) receptor types I and II used in preclinical research to block TGF-β/Smad signaling and study effects on tumor progression and cellular autophagy.

  • Orally active dual inhibitor of TGF-β receptor type I and II.
  • Ki values: TβRI = 38 nM, TβRII = 300 nM (cell-free assays).
  • Molecular formula C26H27N5O2; molar mass ≈ 441.5 g·mol-1.
  • Reported purity up to 99.99% by some vendors; intended for research use only.
  • Used to study Smad2 phosphorylation, autophagy, apoptosis, and metastasis in preclinical models.

Catalog No. 50-002-30400 Supplier Medchemexpress LLC Supplier No. HY12075100MG
May include imposed supplier surcharges.
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LY2109761 is an orally active, small-molecule dual inhibitor of transforming growth factor-β (TGF-β) receptor types I and II used in preclinical research to block TGF-β/Smad signaling and study effects on tumor progression and cellular autophagy.

  • Orally active dual inhibitor of TGF-β receptor type I and II.
  • Ki values: TβRI = 38 nM, TβRII = 300 nM (cell-free assays).
  • Molecular formula C26H27N5O2; molar mass ≈ 441.5 g·mol-1.
  • Reported purity up to 99.99% by some vendors; intended for research use only.
  • Used to study Smad2 phosphorylation, autophagy, apoptosis, and metastasis in preclinical models.

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