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Cayman Chemical 7 27-dIhydroxy Cholesterol 1mg
SDP

Catalog No. 502984834
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An oxysterol and RORγ and RORγt agonist; activates RORγ- or RORγt-dependent signaling in reporter assays using HEK293T cells expressing the recombinant human receptors (EC50s = 691 and 1,0451 nM, respectively); selective for RORγ and RORγt over a panel of eight additional nuclear receptors at 30 µM; increases IL-17A production in Th17-polarized isolated human naïve CD4+ T cells at 300 nM; increases PMA and ionomycin-induced IL-17A production in isolated mouse γδ T cells at 60 mg/kg

Catalog No. 50-298-4834 Supplier Cayman Chemical Supplier No. 201021 MG
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An oxysterol and RORγ and RORγt agonist; activates RORγ- or RORγt-dependent signaling in reporter assays using HEK293T cells expressing the recombinant human receptors (EC50s = 691 and 1,0451 nM, respectively); selective for RORγ and RORγt over a panel of eight additional nuclear receptors at 30 µM; increases IL-17A production in Th17-polarized isolated human naïve CD4+ T cells at 300 nM; increases PMA and ionomycin-induced IL-17A production in isolated mouse γδ T cells at 60 mg/kg

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