Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000421052

Medchemexpress LLC 7,4'-Dihydroxyflavone | 2196-14-7 | 5 MG
SDP

Supplier:  Medchemexpress LLC HYN26095MG

Encompass_Preferred

7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid isolated from *Glycyrrhiza uralensis*. It functions as an eotaxin/CCL11 inhibitor and a CBR1 inhibitor with an IC50 of 0.28 μM. This compound has shown the ability to consistently suppress eotaxin production and prevent the paradoxical adverse effects of dexamethasone on eotaxin production.

  • Inhibits MUC5AC gene expression and mucus production and secretion.
  • Regulates NF-κB, STAT6, and HDAC2.
  • Decreases phorbol 12-myristate 13-acetate (PMA) stimulated MUC5AC gene expression.
  • Reduces mucus production in NCI-H292 human airway epithelial cells with an IC50 value of 1.4 μM.

Catalog No. 50-004-21052


May include imposed supplier surcharges.
Only null left
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.