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Medchemexpress LLC 7,4'-Dihydroxyflavone | 2196-14-7 | MFCD00017694 | 1 ML
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Supplier:  Medchemexpress LLC HYN260910MM/1ML

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7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid isolated from *Glycyrrhiza uralensis*. It acts as an eotaxin/CCL11 inhibitor and a CBR1 inhibitor with an IC50 of 0.28 μM. This compound can consistently suppress eotaxin production and prevent dexamethasone (Dex)‐paradoxical adverse effects on eotaxin production.

  • Inhibits MUC5AC gene expression
  • Reduces mucus production and secretion
  • Regulates NF-κB, STAT6, and HDAC2 pathways
  • Decreases phorbol 12-myristate 13-acetate (PMA) stimulated NCI-H292 human airway epithelial cell MUC5AC gene expression and mucus production with an IC50 value of 1.4 μM

Catalog No. 50-004-20827


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