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Medchemexpress LLC 7,8-Dihydroxyflavone | 38183-03-8 | 254.24 | 25 MG
Supplier: Medchemexpress LLC 25MGHYW013372
7,8-Dihydroxyflavone is a potent and selective TrkB agonist that mimics the physiological actions of Brain-derived neurotrophic factor (BDNF). It displays therapeutic efficacy toward various neurological diseases.
- Protects primary cortical neurons and locus coeruleus neurons from Aβ-induced toxicity
- Promotes dendritic growth and synaptogenesis
- Prevents synaptic loss and memory deficits in an Alzheimer's Disease model
- Activates TrkB in the brain
- Inhibits kainic acid-induced toxicity
- Decreases infarct volumes in stroke
- Neuroprotective in a Parkinson disease model
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