(7-Aza-1H-benzotriazol-1-yloxy)tri(1-pyrrolidinyl)phosphonium hexafluorophosphate, 99+%

Description

CAS: 156311-83-0 | C17H27F6N7OP2 | 521.39 g/mol

(7-Aza-1H-benzotriazol-1-yloxy)tri(1-pyrrolidinyl)phosphonium hexafluorophosphate is used as reagent for synthesis of cyclic RGC pentapeptides for functionalization through click chemistry, fluorescent glucose bioprobes and ReactIR™ flow cell. It is also used as reagent for disulfide bond engineering, heteroaryl ether synthesis and optimization of conformational constraint on non-phosphorylated cyclic peptide antagonists of the Grb2-SH2 domain.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
(7-Aza-1H-benzotriazol-1-yloxy)tri(1-pyrrolidinyl)phosphonium hexafluorophosphate is used as reagent for synthesis of cyclic RGC pentapeptides for functionalization through click chemistry, fluorescent glucose bioprobes and ReactIR™ flow cell. It is also used as reagent for disulfide bond engineering, heteroaryl ether synthesis and optimization of conformational constraint on non-phosphorylated cyclic peptide antagonists of the Grb2-SH2 domain.

Solubility
Soluble in water.

Notes
Stable under recommended storage conditions. Store away from oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 156311-83-0
• Molecular Formula: C17H27F6N7OP2
• Molecular Weight (g/mol): 521.39
• MDL Number: MFCD03703417
• InChI Key: CBZAHNDHLWAZQC-UHFFFAOYSA-N
• Synonym: pyaop, 3h-1,2,3 triazolo 4,5-b pyridin-3-yl oxy tri pyrrolidin-1-yl phosphonium hexafluorophosphate v, 7-azabenzotriazol-1-yloxy tripyrrolidinophosphonium hexafluorophosphate, 3-hydroxy-3h-1,2,3-triazolo 4,5-b pyridinato-o tri-1-pyrrolidinylphosphonium hexafluorophosphate, pyaop reagent, 7-azabenzotriazol-1-yloxy tripyrrolidino-phosphonium hexafluorophosphate, 7-azabenzotriazol-1-yloxy-tris-pyrrolidino phosphonium hexafluorophosphate, pubchem12746, ksc491e1h
• PubChem CID: 11038641
• IUPAC Name: tripyrrolidin-1-yl(triazolo[4,5-b]pyridin-3-yloxy)phosphanium;hexafluorophosphate
• SMILES: F[P-](F)(F)(F)(F)F.C1CCN(C1)[P+](ON1N=NC2=CC=CN=C12)(N1CCCC1)N1CCCC1

• Melting Point: 163°C to 168°C
• Quantity: 5 g
• Solubility Information: Soluble in water.
• Formula Weight: 521.38
• Percent Purity: ≥99%
• Chemical Name or Material: (7-Aza-1H-benzotriazol-1-yloxy)tri(1-pyrrolidinyl)phosphonium hexafluorophosphate

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
RTECSNumber	TH3890000
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only