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Abcam 7-Cl-O-Nec1, metabolically stable RIP1 inhibitor, 5MG

Catalog No. 502587592
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MW 277.7 Da, Purity >98%. Necrostatin-1 (ab141053) analog with superior selectivity and metabolic stability in blocking RIP1. No off-target inhibition of indolamine-2,3-deoxygenase (IDO) in contrast to Necrostatin-1. Higher activity in inhibiting necroptosis in Jurkat cells than Necrostatin-1 (EC₅₀ = 210 nM vs. EC₅₀ = 490 nM).

The product is subject to the following: Abcam Restricted Use Statement

Catalog No. 50-258-7592 Supplier Abcam Supplier No. AB2219845MG
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MW 277.7 Da, Purity >98%. Necrostatin-1 (ab141053) analog with superior selectivity and metabolic stability in blocking RIP1. No off-target inhibition of indolamine-2,3-deoxygenase (IDO) in contrast to Necrostatin-1. Higher activity in inhibiting necroptosis in Jurkat cells than Necrostatin-1 (EC₅₀ = 210 nM vs. EC₅₀ = 490 nM).

The product is subject to the following: Abcam Restricted Use Statement

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