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Cayman Chemical 7-ethoxy-4-MethylcoumarIn 1g

Supplier: Cayman Chemical 195861 G

A PPARa and PPARY dual agonist increases transcriptional activity of PPARa and PPARY in a luciferase reporter assay in AC2F rat liver cells at 5 UM reduces serum glucose triglyceride and insulin levels and improves hepatic steatosis in db/db mice and 20-month-old rats at 3mg/kg reduces peroxynitrite and COX-2 levels ROS production and Akt phosphorylation in 20-month-old rat kidney at 3 mg/kg inhibits mushroom tyrosinase (IC50 8 19 UM) inhibits increases in melanin content in a-melanocyte stimulating hormone-induced B16/F10 murine melanoma cells at 10 UM
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