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Medchemexpress LLC 7-Hydroxyflavone | 6665-86-7 | 1 ML
Supplier: Medchemexpress LLC HYN710810MM/1ML
7-Hydroxyflavone is a flavonoid isolated from *Clerodendrum phlomidis* that exhibits anti-inflammatory activity. It protects renal cells from nicotine-associated cytotoxicity through the ERK/Nrf2/HO-1 pathway. This compound inhibits PKM2, COX-2, and 5-LOX, and is orally active.
- Inhibits nicotine-induced cytotoxicity and reduces ROS production in renal cells
- Inhibits EV71 3C protease, blocking viral replication
- Decreases malondialdehyde and ROS levels, increases SOD and GSH levels in HepG2 cells
- Inhibits inflammatory cytokines and reduces myocardial injury markers in rat models
- Ameliorates Paclitaxel or Vinorelbine-induced neuropathic pain in mice models
- Reduces fat accumulation, improves hepatic steatosis and oxidative stress in NAFLD models
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