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Medchemexpress LLC 7-Hydroxyflavone | 6665-86-7 | 10 MG
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Catalog No. 5000418995
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7-Hydroxyflavone is a flavonoid isolated from *Clerodendrum phlomidis* with anti-inflammatory activity. It protects renal cells from nicotine (NIC)-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway. This compound inhibits PKM2 with an IC50 of 2.12 μM and also inhibits COX-2 and 5-LOX with IC50s of 27 μg/mL and 33 μg/mL, respectively. 7-Hydroxyflavone is orally active.

  • Isolated from *Clerodendrum phlomidis*.
  • Exhibits anti-inflammatory activity.
  • Protects renal cells from nicotine-associated cytotoxicity.
  • Inhibits PKM2, COX-2, and 5-LOX.
  • Orally active.
  • Inhibits EV71 3C protease and viral replication.
  • Antioxidant properties: decreases MDA and ROS, increases SOD and GSH.
  • Ameliorates ischemia/reperfusion injury and neuropathic pain.
  • Improves hepatic steatosis and regulates blood glucose metabolism in NAFLD models.

Catalog No. 50-004-18995 Supplier Medchemexpress LLC Supplier No. HYN710810MG
May include imposed supplier surcharges.
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7-Hydroxyflavone is a flavonoid isolated from *Clerodendrum phlomidis* with anti-inflammatory activity. It protects renal cells from nicotine (NIC)-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway. This compound inhibits PKM2 with an IC50 of 2.12 μM and also inhibits COX-2 and 5-LOX with IC50s of 27 μg/mL and 33 μg/mL, respectively. 7-Hydroxyflavone is orally active.

  • Isolated from *Clerodendrum phlomidis*.
  • Exhibits anti-inflammatory activity.
  • Protects renal cells from nicotine-associated cytotoxicity.
  • Inhibits PKM2, COX-2, and 5-LOX.
  • Orally active.
  • Inhibits EV71 3C protease and viral replication.
  • Antioxidant properties: decreases MDA and ROS, increases SOD and GSH.
  • Ameliorates ischemia/reperfusion injury and neuropathic pain.
  • Improves hepatic steatosis and regulates blood glucose metabolism in NAFLD models.

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