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Medchemexpress LLC 7-Hydroxyflavone | 6665-86-7 | 100 MG

Supplier: Medchemexpress LLC HYN7108100MG
7-Hydroxyflavone is a flavonoid isolated from *Clerodendrum phlomidis*, demonstrating anti-inflammatory activity. It protects renal cells from nicotine (NIC)-associated cytotoxicity through the ERK/Nrf2/HO-1 pathway, and inhibits PKM2, COX-2, and 5-LOX. This compound is orally active.
- Isolated from *Clerodendrum phlomidis*
- Protects renal cells from nicotine-associated cytotoxicity
- Inhibits PKM2 with an IC50 of 2.12 μM
- Inhibits COX-2 and 5-LOX with IC50s of 27 μg/mL and 33 μg/mL
- Orally active
- Ameliorates neuropathic pain in mice models
- Improves high-fat diet-induced non-alcoholic fatty liver disease
- Reduces malondialdehyde (MDA) and ROS levels in HepG2 cells
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