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Apexbio Technology LLC 7-Methoxycoumarin-4-acetyl-P-L-G-L-β-(2,4-dinitrophenylamino)A-R amide 140430-53-1 5mg
Supplier: Apexbio Technology LLC A15005
7-Methoxycoumarin-4-acetyl-P-L-G-L-beta-24-dinitrophenylamino A-R amide (CAS 140430-53-1) is a fluorogenic peptide substrate targeting matrix metalloproteinases (MMPs) It is designed to enable the continuous measurement of MMP enzymatic activity which is achieved by monitoring substrate cleavage between Gly and Leu residues 7-Methoxycoumarin-4-acetyl-P-L-G-L-beta-24-dinitrophenylamino A-R amide exerts its utility through a fluorescence-based mechanism cleavage by MMPs separates the fluorescent reporter group from the quencher resulting in increased fluorescence signal Based on these properties 7-Methoxycoumarin-4-acetyl-P-L-G-L-beta-24-dinitrophenylamino A-R amide is employed in biochemical assays for the quantification of total or specific MMP activity in biological samples and enzyme preparations
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