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Cayman Chemical 7-methyl DMT 1mg
Supplier: Cayman Chemical 416841 MG
An anticancer peptide fragment of LL-37 inhibits the ATPase activity of ABCG2 at 1 UM induces cytotoxicity in wild-type SW620 cells and SW620 cells overexpressing P-gp (IC50s 25.5 and 27.3 UM respectively) as well as wild-type MCF-7 cells MCF-7 cells overexpressing ABCG2 and MCF-7 cells overexpressing MRP1 (IC50s 33.1 31.8 and 31.1 UM respectively) potentiates mitoxantrone-induced cytotoxicity in MCF-7 and HEK293 cells overexpressing ABCG2 at 5 or 10 UM decreases mitoxantrone drug efflux by and increases mitoxantrone levels in MCF-7 cells overexpressing ABCG2 at 10 20 or 40 UM
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