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Medchemexpress LLC 7-Nitroindazole | 2942-42-9 | 99.1% | C7H5N3O2 | 500 MG
Supplier: Medchemexpress LLC HY69019500MG
7-Nitroindazole is a selective and BBB-penetrable inhibitor of nitric oxide synthase (NOS) with anti-injurious and neuroprotective properties, making it useful for research into neurological diseases such as Parkinson's disease.
- Selective and BBB-penetrable inhibitor of nitric oxide synthase (NOS).
- Inhibits nNOS in experimental animals without affecting blood pressure or endothelium-dependent relaxation.
- Exhibits anti-injurious and anti-nociceptive effects in a formalin-induced mouse pain model.
- Improves L-DOPA-induced dyskinesias in non-human primate models of Parkinson's disease.
- Enhances learning and memory in hypothyroid rats.
- Potentiates c-fos expression induced by muscle proprioceptive signaling in the spinal cord.
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