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Cayman Chemical 7a-hydroxy Cholesterol 5mg
Supplier: Cayman Chemical 200985 MG
An oxysterol and a precursor in the biosynthesis of CA and CDCA; formed via the oxidation of cholesterol by CYP7A1 in rat liver microsomes; increases ICAM-1, VCAM-1, and E-selectin levels in HUVECs at 40 µM; increases secretion of CCL2 and MMP-9 in serum-deprived THP-1 cells at 5 UG/ml; has been found in macrophages isolated from atherosclerotic lesions in rabbits fed a high-cholesterol diet
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