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Apexbio Technology LLC 7ACC1 50995-74-9 100mg
Supplier: Apexbio Technology LLC B4867100
7ACC1 (CAS 50995-74-9) also known as DEAC or Coumarin D1421 is a selective inhibitor of monocarboxylate transporters MCT-1 and MCT-4 which facilitate lactate transmembrane transport By blocking these transporters 7ACC1 disrupts cellular lactate efflux and modulates the metabolic environment of tumor cells In vitro studies demonstrate that treatment with 7ACC1 reduces lactate secretion in renal cancer cells accompanied by decreased cell proliferation migration and invasion as well as downregulation of MCT-1 and MCT-4 protein expression 7ACC1 is a useful tool for investigating tumor metabolism and the mechanisms underlying tumor growth and metastasis
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