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AdipoGen 7DW8-5
SDP

Supplier:  AdipoGen AGCN20519C500

Encompass_Preferred

Chemical. CAS 1056025-00-3. Formula C41H72FNO9. MW 742. . Glycolipid derivative of alpha-GalCer. Potent stimulator of invariant natural killer T iNKT cells 140-fold lower EC50 compared to alpha-GalCer. Specific ligand strongest binding affinity of the lipid-binding MHC class I-like protein CD1d in human and mouse NKT cells with. Show to induce secretion of key cytokines such as IFN-gamma and IL-12, and activate autologous dendritic cells, as well as binding to CD1d and the invariant T cell receptor invTCR. Potent vaccine adjuvant ~100 times stronger than alpha-GalCer that can harness and amplify the immunotherapeutic potential of NKT cells to treat certain microbial infections such as malaria and HIV. Potential immunotherapeutic to treat cancer, infectious diseases and autoimmune diseases.

Catalog No. 50-256-2499


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