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Leica Biosystems 7ml CD103 (EP206) Bond RTU Pri
Supplier: Leica Biosystems PA0374U
Antigen BackgroundCD13, also known as alpha E integrin & human mucosal lymphocyte antigen 1, is an integrin protein with expression on intraepithelial T cells & some peripheral regulatory T cells. CD13 is expressed at high levels on tumour-infiltrating FOXP3-positive regulatory T cells in cancer and CD13-positive T cells are strongly associated with patient survival in high-grade serous ovarian cancer.CD13 expression has been suggested as a definitive marker of intraepithelial, tumour-specific infiltrating lymphocytes. In addition, CD13-positive cells have also been identified in a small proportion of breast cancers.DisclaimerCD13 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.
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