Learn More
Leica Biosystems 7mL PD-1 (CAL20) BOND RTU Prim
Supplier: Leica Biosystems PA0216U
Antigen BackgroundPD-1 (Programmed Death 1) is a 55KDa Type I transmembrane cell surface receptor which is expressed by T-cells during activation. It is also upregulated in B-cells, dendritic cells, natural killer cells and some myeloid cells, suggesting a broad role for PD1 in immune regulation. PD-1 interacts with at least two ligands: PD-L1 and PD-L2. PD-1/PD-L1 interaction is important in many Tcell functions including acute and chronic inflammation, cancer and immunotherapy.DisclaimerPD-1 is recommended for the detection of specific antigens of interest in normal and neoplastic tissues, as an adjunct to conventional histopathology using non-immunologic histochemical stains.
Description
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.