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Medchemexpress LLC 8-(3-chloro-5-(1-methyl-1H-indazol-5-yl)-1H-pyrazolo[3,4-b]pyridin-4-yl)-2,8-diazaspiro[4.5]decan-1- | 2648453-53-4 | 98.9% | C22H22ClN7O | 10MG
SDP

Supplier:  Medchemexpress LLC HY13987510MG

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JH-XVI-178 is a potent, selective small-molecule inhibitor of cyclin-dependent kinases CDK8 and CDK19 for research use. It exhibits low-nanomolar potency and is provided as a purified solid suitable for biochemical assays, cell-based studies, and target validation experiments.

  • Selective inhibition of CDK8 and CDK19, IC50 1 nM and 2 nM respectively.
  • High purity (98.9%).
  • Molecular formula C22H22ClN7O; molecular weight 435.91 g·mol⁻¹.
  • Supplied as a powder with recommended storage for stability.
  • Suitable for biochemical kinase assays and cell-based pharmacology studies.

Catalog No. 50-002-58277


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