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8-(3-Chlorostyryl)caffeine, Tocris Bioscience™

Catalog No. 330650
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Catalog No. Quantity
33-065-0 50 mg
33-061-0 10 mg
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Catalog No. 33-065-0 Supplier R&D Systems Supplier No. 3306/50
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Selective A2A antagonist. Also MAO-B inhibitor

Selective adenosine A2A receptor antagonist and monoamine oxidase B (MAO-B) inhibitor (Ki values are 54 and 28200 nM at rat A2A and A1 receptors respectively and Ki ∽ 100 nM at MAO-B). Potently protects against quinolinic acid -induced (Cat. No. 0225) neuronal damage and is neuroprotective in the MPTP model of Parkinson's disease.

Chemical Identifiers

CAS 147700-11-6
Molecular Formula C32H30Cl2N8O4
Molecular Weight (g/mol) 661.544
InChI Key YMUNFKYGBSLPLQ-UHFFFAOYSA-N
Synonym 1h-purine-2,6-dione,8-1e-2-3-chlorophenyl ethenyl-3,7-dihydro-1,3,7-trimethyl, acmc-20n59d
PubChem CID 57348597
IUPAC Name 8-[2-(3-chlorophenyl)ethenyl]-1,3,7-trimethylpurine-2,6-dione
SMILES CN1C(=NC2=C1C(=O)N(C(=O)N2C)C)C=CC3=CC(=CC=C3)Cl.CN1C(=NC2=C1C(=O)N(C(=O)N2C)C)C=CC3=CC(=CC=C3)Cl

Specifications

Quantity 50 mg
Formula Weight 330.77
Percent Purity >99%
Chemical Name or Material 8-(3-Chlorostyryl)caffeine
Recommended Storage Store at -20°C
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