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Cayman Chemical 8- 3-ChlorostyrylcaffeIn 10mg

Supplier: Cayman Chemical 2970410 MG
An adenosine A2 receptor antagonist (Ki = 54 nM); selective for adenosine A2 over A1 receptors (Ki = 28 µM); reverses APEC-induced locomotor depression in mice (ED50 = 16 UG/kg, i.p.); increases locomotion in mice at 5 mg/kg; reverses L-DOPA-induced shortening of the rotational motor response and increases in striatal adenosine A2 receptor levels in a rat model of 6-OHDA-induced Parkinson's disease at 5 mg/kg; inhibits MAO-B (Ki = 100 nM); reduces MAO-B activity in brain mitochondrial preparations from wild-type and A2A-/- mice
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