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Cayman Chemical 8- 3-ChlorostyrylcaffeIn 50mg
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Supplier:  Cayman Chemical 2970450 MG

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A bivalent Smac mimetic and IAP antagonist binds to IAP1 and XIAP (Kds 0 46 and 1 3 nM respectively) induces autoubiquitination and proteasomal degradation of IAP1 and XIAP in MDA-MB-231 cells at 5 M induces NF-KB activation and TNF-dependent apoptosis in A2058 and MDA-MB-231 cells at 4 M enhances radiosensitization and increases apoptosis in HCC193 and H460 NSCLC cell lines induces cell death in a panel of 40 primary patient-derived BCP-ALL samples at 1 M increases survival and time to relapse in a high-risk BCP-ALL PDX mouse model

Catalog No. 50-298-9128


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