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Medchemexpress LLC 8-(4-(trifluoromethyl)phenyl)-N-(1,1,1-trifluoropropan-2-yl)-dihydro-1,7-naphthyridine carboxamide | 1470018-52-0 | >98.0% | 417.3 g·mol^-1 | C19H17F6N3O | 100 MG
SDP

Supplier:  Medchemexpress LLC HY104059100MG

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AMG2850 is a selective, orally bioavailable antagonist of the transient receptor potential melastatin 8 (TRPM8) ion channel. Synthesized at Amgen and characterized in peer-reviewed literature, it inhibits menthol- and cold-induced TRPM8 activation and is used as a research reagent in preclinical pharmacology and TRP channel studies.

  • Potent inhibition of menthol- and cold-induced TRPM8 activation.
  • High selectivity over other TRP channels.
  • Orally bioavailable pharmacokinetic profile suitable for in vivo studies.
  • Reported high chemical purity, suitable for research applications.
  • Used and validated in peer-reviewed preclinical studies.

Catalog No. 50-002-42862


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