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Apexbio Technology LLC 8-Azido-ATP(Synonyms: 8-Azidoadenosine 5'-triphosphate, 8-N3-ATP, 8-Azido-ATP, 8-Azidoadenosine triphosphate), 50ul (100 mM).
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Supplier:  Apexbio Technology LLC B80320.05

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8-Azido-ATP is a ribonucleoside triphosphate analog with an azido group substitution at the adenine C-8 position It acts primarily as an ATP mimic interacting with poly(A) polymerase (PAP) specifically illustrated using yeast poly(A) polymerase (yPAP) Incorporation of 8-azido-ATP into growing polyadenylation chains results in premature termination and moderately shorter poly(A) tails relative to natural ATP substrates Due to its chain-terminating capacity and altered substrate specificity 8-azido-ATP is applied in biochemical studies examining enzyme fidelity nucleotide selection mechanisms and RNA polymerase activity

Catalog No. 50-000-60700


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