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Apexbio Technology LLC 8-Bromo-cAMP sodium salt 25mg
Supplier: Apexbio Technology LLC B900025
8-Bromo-cAMP sodium salt (CAS 76939-46-3) is a synthetic cyclic AMP analogue that influences various signal transduction pathways It primarily activates protein kinase A (PKA) and can trigger phosphorylation cascades such as ERK1/2 activation independently of Shc phosphorylation In diverse cell types this molecule modulates gene expression for instance increasing mRNA levels for chorionic gonadotropin subunits and reducing fibronectin mRNA It also enhances catecholamine synthesis via tyrosine hydroxylase phosphorylation Thus 8-Bromo-cAMP serves as a valuable reagent for examining cellular proliferation differentiation and hormonal regulation mechanisms
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