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Cayman Chemical 8-bromo CyclIc AMP 100mg
Supplier: Cayman Chemical 18141100 MG
A PKA activator (Ka = 0.05 µM); selective for PKA over PKG (Ka = 5.8 µM); more resistant to hydrolysis by PDEs than cAMP; inhibits the proliferation of HL-60 cells (IC50 = 18 µM after six days); induces relaxation of phenylephrine-precontracted isolated rabbit carotid or renal arterial rings at 10-300 µM; intradermal administration prevents SLIGRL-NH2-induced scratching and increases in cutaneous LTB4 production in mice at 10 nmol/site
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