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Medchemexpress LLC 8-chloro-11-(4-ethylpiperazin-1-yl)-4-fluoro-5H-dibenzo[b,e]diazepine | 2369979-68-8 | 100.0% | 358.84 g/mol | C19H20ClFN4 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1318815MG

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JHU37160 is a brain-penetrant DREADD agonist for chemogenetic research, showing potent activity at engineered muscarinic DREADDs and selective displacement of clozapine binding. It is provided as a solid (white to yellow) with reported high purity and recommended storage conditions for powder and solutions, suitable for in vitro and in vivo DREADD modulation studies.

  • Potent DREADD agonist with low-nanomolar EC50s (hM3Dq and hM4Di)
  • Brain-penetrant for in vivo applications
  • Selective displacement of [3H]clozapine from DREADDs
  • High reported purity suitable for research use
  • Supplied as a solid with specified storage conditions
  • Available in multiple small pack sizes and as a DMSO solution

Catalog No. 50-002-62600


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