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Medchemexpress LLC 8-CPT-Cyclic AMP sodium | 93882-12-3 | 99.7% | 493.79 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY111673100MG

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8-CPT-Cyclic AMP sodium is a selective activator of cyclic AMP-dependent protein kinase (PKA). It is also a potent inhibitor of the cyclic GMP-specific phosphodiesterase (PDE VA) with an IC50 of 0.9 μM, and it inhibits PDE III and PDE IV with IC50Epac, functioning as a potent Epac activator.

  • Delays TNF-α/CHX-induced and α-Fas-induced apoptosis in neutrophils.
  • More effective against apoptosis induced by TNF-α/CHX than by α-Fas.

Catalog No. 50-004-39136


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