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Medchemexpress LLC 8-Hydroxyquinoline | 148-24-3 | 99.95% | 1 G

Supplier: Medchemexpress LLC HYB10051G
8-Hydroxyquinoline (8-Quinolinol) is a lipophilic metal chelator used as a fungicide. It demonstrates an MIC range of 27.56-55.11 μM (4-8 μg/mL) against clinical isolates of *Neisseria gonorrhoeae*. The compound binds to copper, forming complexes that facilitate copper transport into cells. It has also been observed to increase micronucleated polychromatic erythrocytes and cause hair depigmentation in mice. This product is for research use only and is not sold to patients.
- Functions as a lipophilic metal chelator and fungicide
- Exhibits activity against *Neisseria gonorrhoeae*
- Binds to copper to facilitate cellular transport
- Increases micronucleated polychromatic erythrocytes in mice
- May cause hair depigmentation in mice
- Induces cytotoxicity in various cell lines
- Inhibits proteasomal chymotrypsin-like activity
- Reduces inflammation by inhibiting NO production and iNOS expression
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