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AdipoGen 8-Methoxypsoralen
SDP

Supplier:  AdipoGen CDXM0156G005

Encompass_Preferred

Chemical. CAS 298-81-7. Formula C12H8O4. MW 216.19. Synthetic. Methoxsalen 8-Methoxypsoralen is a potent tricyclic furocoumarin suicide inhibitor of CYP cytochrome P-450. Has more potency than 5-MOP, 5-OH-P, DH-8-MOP and psoralen in inhibiting CYP2B1 cytochrome P-450 2B1. Completely inhibits the metabolism of nicotine in vitro. Inhibits the metabolism of caffeine. Methoxsalen is a drug with photoactivating properties used to treat psoriasis, eczema, vitiligo and some cutaneous lymphomas in conjunction with exposing the skin to UVA light. Upon photoactivation, ultraviolet A UVA irradiation induces monoadducts and interstrand cross-links in DNA and therefore can be used to study DNA repair and recombination mechanisms.

Catalog No. 50-256-0487


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