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Medchemexpress LLC 8-OH-DPAT | 78950-78-4 | 99.87% | 247.38 | 100 MG
SDP

Catalog No. 5000439368
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8-OH-DPAT is a potent, brain-penetrant, and selective 5-HT agonist. It exhibits a pIC50 of 8.19 for 5-HT1A and a Ki of 466 nM for 5-HT7. It binds weakly to 5-HT1B (pIC50, 5.42) and 5-HT (pIC50 <5). For research use only.

  • Potent, brain-penetrant, and selective 5-HT agonist.
  • High affinity for 5-HT1A (pIC50 8.19) and 5-HT7 (Ki 466 nM).
  • Weakly binds to 5-HT1B (pIC50 5.42) and 5-HT (pIC50 <5). Does not bind to 5-HT6 or 5-HT4.
  • Normalizes hypolocomotion, increases wakefulness, and reduces REM sleep duration in orexin knockout (KO) mice, activating the 5-HT1A receptor.
  • Solid, white to light brown appearance.

Catalog No. 50-004-39368 Supplier Medchemexpress LLC Supplier No. HY112061100MG
May include imposed supplier surcharges.
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8-OH-DPAT is a potent, brain-penetrant, and selective 5-HT agonist. It exhibits a pIC50 of 8.19 for 5-HT1A and a Ki of 466 nM for 5-HT7. It binds weakly to 5-HT1B (pIC50, 5.42) and 5-HT (pIC50 <5). For research use only.

  • Potent, brain-penetrant, and selective 5-HT agonist.
  • High affinity for 5-HT1A (pIC50 8.19) and 5-HT7 (Ki 466 nM).
  • Weakly binds to 5-HT1B (pIC50 5.42) and 5-HT (pIC50 <5). Does not bind to 5-HT6 or 5-HT4.
  • Normalizes hypolocomotion, increases wakefulness, and reduces REM sleep duration in orexin knockout (KO) mice, activating the 5-HT1A receptor.
  • Solid, white to light brown appearance.

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