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Medchemexpress LLC 9,12-Octadecadienoic acid (9Z,12Z)-, 2-hydroxy-1-(hydroxymethyl)ethyl ester | 3443-82-1 | 99.9% | 500 UG
Supplier: Medchemexpress LLC HY130311500UG
2-Linoleoyl glycerol is a monoacylglycerol that acts as an antagonist and partial agonist at the type 1 cannabinoid CB1 receptor. Its potency can be increased by JZL195, an inhibitor of FAAH and MAGL, and decreased by the CB1 antagonist AM251 and Cannabidiol. As a CB1 antagonist, 2-Linoleoyl glycerol does not enhance, but only attenuates, the activity of the CB1/CB2 receptor ligands such as cannabinoids (AEA) and 2-arachidonoylglycerol (2-AG). It is for research use only.
- Acts as an antagonist and partial agonist at the type 1 cannabinoid CB1 receptor
- Potency increased by JZL195, an inhibitor of FAAH and MAGL
- Activity decreased by the CB1 antagonist AM251 and Cannabidiol
- Attenuates the activity of CB1/CB2 receptor ligands
- Molecular weight: 354.52
- Formula: C21H38O4
- Appearance: Liquid, colorless to light yellow
- Storage: Solution, -20°C, 2 years
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