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Medchemexpress LLC 9-Aminoacridine | 90-45-9 | 99.4% | 250 MG
Supplier: Medchemexpress LLC 250MGHYB1422
9-Aminoacridine is a fluorescent probe functioning as a pH indicator for quantitative determination of transmembrane pH gradients. It also acts as an antimicrobial by interacting with bacterial DNA and disrupting the proton motive force in K. pneumoniae. Furthermore, it is an HIV-1 inhibitor, suppressing HIV LTR transcription and virus replication in infected cell lines, and can serve as a Rifampin adjuvant for multidrug-resistant K. pneumoniae infections.
- Acts as a fluorescent pH indicator.
- Antimicrobial effect against K. pneumoniae.
- Inhibits HIV-1 LTR transcription and virus replication.
- Can be used as a Rifampin adjuvant.
- Shows moderate cytotoxicity to human cell lines.
- Decreases abscess area in skin subcutaneous abscess mice model.
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