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Apexbio Technology LLC 9-cis-Retinoic Acid 5300-03-8 25mg
Supplier: Apexbio Technology LLC C374225
9-cis-Retinoic Acid (CAS 5300-03-8) is a small-molecule agonist targeting retinoic acid receptors (RARs) and retinoid X receptors (RXRs) It is designed to activate these nuclear receptors thereby regulating transcription of genes involved in cell differentiation immune responses neural function proliferation and reproduction 9-cis-Retinoic Acid exerts its biological activity primarily through RAR/RXR-mediated gene regulation In in vitro studies 9-cis-Retinoic Acid modulates expression of myotrophin (Mptn) and miR-375 in pancreatic -cell and breast cancer cell lines It exhibits nanomolar binding affinity to RAR (Ki 0 5 27 nM) and RXR (Ki 3 8 12 nM) Based on these pharmacological properties 9-cis-Retinoic Acid holds research potential in oncology immunomodulation neuroprotection and dermatological conditions
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