Medchemexpress LLC 9-Decyn-1-ol | 17643-36-6 | 100 G

Supplier:  Medchemexpress LLC HY130985100G

9-Decyn-1-ol is an alkyl/ether-based PROTAC linker used in the synthesis of PROTACs. It can be employed to conjugate GDC-0068 with Lenalidomide, resulting in INY-03-041, a potent, highly selective, and PROTAC-based pan-Akt degrader. It also functions as a click chemistry reagent.

• Used in the synthesis of PROTACs
• Can conjugate GDC-0068 with Lenalidomide to create INY-03-041, a pan-Akt degrader
• Inhibits Akt1, Akt2, and Akt3 with IC50s of 2.0 nM, 6.8 nM, and 3.5 nM, respectively
• Click chemistry reagent containing an Alkyne group
• Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups

Catalog No. 50-003-40312