Medchemexpress LLC 9-ethyl-3-(5-phenyl-1H-1,2,3-triazol-1-yl)-9H-carbazole | 2097938-73-1 | 99.9% | 338.41 | 50 MG

Supplier:  Medchemexpress LLC HY11284250MG

MBQ-167 is a dual Rac/Cdc42 inhibitor with potential antineoplastic activity, targeting Rac and Cdc42, which are overexpressed in various cancers. It inhibits p21-activated kinase (PAK) and STAT3 signaling, inducing cell-cycle arrest and apoptosis, and inhibiting cancer cell proliferation and migration. It also reduces tumor-infiltrating macrophages and myeloid-derived suppressor cells (MDSCs) in the tumor microenvironment, demonstrating significant reduction in tumor growth in vivo.

• Dual Rac/Cdc42 inhibitor
• Targets and inhibits Rac and Cdc42 activity
• Inhibits p21-activated kinase (PAK) and STAT3 signaling
• Induces cell-cycle arrest and apoptosis
• Inhibits cancer cell proliferation and migration
• Reduces tumor-infiltrating macrophages and myeloid-derived suppressor cells
• Demonstrates significant reduction in tumor growth in vivo

Catalog No. 50-004-38498