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Medchemexpress LLC 9-Hydroxyphenanthrene | 484-17-3 | 98.6% | 194.23 | 250 MG
Supplier: Medchemexpress LLC 250MGHY108457
9-Phenanthrol (9-Hydroxyphenanthrene) is a selective TRPM4 inhibitor with an IC50 of 17 μM. It demonstrates no inhibitory activity on TRPM5, TRPC6, and CFTR. This compound can be utilized for research into ischemia-reperfusion injury, with studies showing it can reduce myocardial dysfunction in isolated rat hearts subjected to ischemia and reperfusion.
- Selective TRPM4 inhibitor with an IC50 of 17 μM.
- Shows no inhibitory activity on TRPM5, TRPC6, and CFTR.
- Useful for research into ischemia-reperfusion injury.
- Can reduce myocardial dysfunction in isolated rat hearts.
- Leads to significant improvement in heart function.
- Reduces infarct size in affected hearts.
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