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Cell Biolabs Inc CytoSelect™ 96-Well Anoikis Assay Kit (Colorimetri/Fluorometric)

Catalog No. 501098820
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Adhesion to the extracellular matrix is essential for the survival of many adherent cells. Apoptosis that results from the loss of cell adhesion to the ECM, or inappropriate adhesion, is defined as “anoikis”. A common feature of carcinoma development is the ability of transformed cells to survive under anchorage independent or “spheroid” growth conditions. Resistance to anoikis has been shown to be involved in the loss of cell homeostasis, cancer growth, and metastasis. Preventing anoikis is a major goal in the development of cell transplantation techniques, including the therapeutic use of progenitor cells. The CytoSelect™ 96-well Anoikis Assay Kit provides a colorimetric and fluorometric format to measure anchorage-independent growth and monitoring anoikis propelled cell death. The kit contains sufficient reagents for 96 samples in a hydrogel-coated 96-well plate. Live cells are detected with MTT or Calcein AM. Cell death is detected with the Ethidium Homodimer (EthD-1).

Catalog No. 50-109-8820 Supplier Cell Biolabs Inc Supplier No. CBA081
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Adhesion to the extracellular matrix is essential for the survival of many adherent cells. Apoptosis that results from the loss of cell adhesion to the ECM, or inappropriate adhesion, is defined as “anoikis”. A common feature of carcinoma development is the ability of transformed cells to survive under anchorage independent or “spheroid” growth conditions. Resistance to anoikis has been shown to be involved in the loss of cell homeostasis, cancer growth, and metastasis. Preventing anoikis is a major goal in the development of cell transplantation techniques, including the therapeutic use of progenitor cells. The CytoSelect™ 96-well Anoikis Assay Kit provides a colorimetric and fluorometric format to measure anchorage-independent growth and monitoring anoikis propelled cell death. The kit contains sufficient reagents for 96 samples in a hydrogel-coated 96-well plate. Live cells are detected with MTT or Calcein AM. Cell death is detected with the Ethidium Homodimer (EthD-1).

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