Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC A 438079 | 899507-36-9 | C13H9Cl2N5 | 100 MG
Supplier: Medchemexpress LLC HY15488100MG
A 438079 is a potent and selective P2X7 receptor antagonist with a pIC50 of 6.9. It is identified by CAS number 899507-36-9 and chemical formula C13H9Cl2N5.
- Potent and selective P2X7 receptor antagonist
- Blocks BzATP-evoked changes in intracellular calcium concentrations
- Reduces noxious and innocuous evoked activity of spinal neurons in neuropathic rats
- Raises withdrawal thresholds in SNL and CCI models
- Reduces seizure severity and neuronal death within the hippocampus
- Partially prevents 6-OHDA-induced depletion of striatal DA stores
- Reduces nociceptive behavior in the HC model
- Provided as a white to off-white solid with 99.88% purity
- Stable as powder at -20°C for 3 years or 4°C for 2 years
- Stable in solvent at -80°C for 2 years or -20°C for 1 year
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?