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Medchemexpress LLC A 438079 hydrochloride | 899431-18-6 | C13H10Cl3N5 | 50 MG
Supplier: Medchemexpress LLC HY15488A50MG
A 438079 hydrochloride is a potent and selective P2X7 receptor antagonist with a pIC50 of 6.9. It is intended for research use only and not sold to patients. This compound is a white to off-white solid with 99.99% purity.
- Potent and selective P2X7 receptor antagonist
- pIC50 of 6.9
- For research use only
- High purity (99.99%)
- White to off-white solid
- Reduces noxious and innocuous evoked activity in neuropathic rats
- Raises withdrawal thresholds in SNL and CCI models
- Reduces seizure severity and neuronal death in the hippocampus
- Prevents depletion of striatal DA stores
- Reduces nociceptive behaviour scores
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