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Medchemexpress LLC A-674563 hydrochloride | 2070009-66-2 | 99.9% | C22H23ClN4O | 10MG
Supplier: Medchemexpress LLC HY13254A10MG
A-674563 hydrochloride is a potent, selective Akt1 (protein kinase B) inhibitor with a reported Ki of 11 nM. It shows in vitro anti-proliferative and pro-apoptotic activity across multiple cancer cell lines and has been used in vivo to investigate Akt-dependent signaling and combination therapies.
- Potent Akt1 inhibition (Ki ≈11 nM).
- High purity suitable for research use (≈99.9%).
- Demonstrated antiproliferative activity in tumor cell assays (EC50 ≈0.4 μM).
- Effective in in vivo models for studying Akt signaling and combination regimens.
- Available as solid and DMSO solution formats for flexible dosing.
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