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Apexbio Technology LLC A 779 159432-28-7 1mg
Supplier: Apexbio Technology LLC B60561
A 779 (CAS 159432-28-7) is a selective antagonist of the angiotensin-(1-7)/Mas receptor By competitively inhibiting angiotensin-(1-7) a bioactive peptide of the renin-angiotensin system (RAS) involved in cardiovascular and renal homeostasis A 779 enables detailed study of Mas receptor-mediated signaling In vivo A 779 blocks the antidiuretic and pressor effects of angiotensin-(1-7) in rats and modulates the response to bradykinin potentiation by ACE inhibition It has been used to explore interactions among angiotensin receptors and the role of Mas signaling in cardiovascular and renal physiology
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