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AG Scientific Inc A 83-01, 5 MG

Supplier:  AG Scientific Inc A17645MG

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A83-01 is a selective inhibitor of TGF-type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 (IC values are 12, 45 and 7.5 nM respectively). Blocks phosphorylation of Smad2 and inhibits TGF-induced epithelial-to-mesenchymal transition. Helps maintain homogeneity and long-term in vitro self-renewal of human induced pluripotent stem cells (iPSCs)Not for human therapeutic use or for medicinal purposes.CAS Number: 909910-43-6Molecular Weight: 421.52Chemical Formula: C25H19N5SSolubility: DMSO (50 mM)Storage Temperature: -20CResearch or further manufacturing use only, not for food or drug use.

Catalog No. 50-223-7021


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