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Abcam A 83-01, ALK4, 5 and 7 kinase inhibitor, 1MG
Supplier: Abcam AB1420921MG
MW 421.5 Da, Purity >98%. Potent, selective TGF-β type I receptor ALK5, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7 kinase inhibitor (IC₅₀ values are 12, 45 and 7.5 nM for ALK5, ALK4 and ALK7 respectively). TGF-β1 inhibitor. Inhibits TGF-β1-dependent α-SMA and collagen type I induction. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
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