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Bachem PyOxim
Supplier: Bachem 4071639.0100
PyOxim, (Ethyl cyano(hydroxyimino)acetato-O2)-tri-(1-pyrrolidinyl)-phosphonium hexafluorophosphate, 153433-21-7, C17H29F6N5O3P2, Mr 527.39, 100g. A highly efficient coupling reagent. PyOxim is more reactive than TBTU or PyBOP. It is about as reactive as COMU; and, as COMU, PyOxim is safer to handle and less allergenic than HOBt-based coupling reagents. As PyOxim represents a phosphonium-type coupling reagent, N-terminal guanidinylation as a side-reaction during coupling is avoided.
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