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Cayman Chemical a-hydroxy Farnesyl Phosphonic
Supplier: Cayman Chemical 634201 MG
α-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl transferase (FTase).{1199,5456} At concentrations greater than 1 µM, α-hydroxy farnesyl phosphonic acid inhibits the processing of Ras in Ha-ras-transformed NIH3T3 cells.{1196}
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